ONGOING PROJECTS

Enabling wearable technologies for individuals experiencing disability.

According to the World Health Organization (WHO) more than a billion people, 15% of the world population, experience disability. It is expected that their number will continue to increase due to chronic health conditions and age. Although disability due to trauma or disease occurs in a wide socio-economic spectrum, two specific groups are overly represented in the low-income communities, due to social and economic factors: individuals with reduced mobility (due to spinal cord injury, stroke, cerebral palsy or limb loss) and individuals with extreme obesity (BMI > 40). The specific health needs of these groups will require a concerted, transdisciplinary effort for diagnosis and treatment.


The PATHS-UP team at FIU is working on better understanding the need of this community

We are designing new wearable and cuffless BP, PPG and muscle oximetry monitors for the obese. Standard metabolic measurements such as blood pressure, heart rate, pulse oximetry, and others cannot be achieved with commercially avalable tools in the obese and extremely obese population. Similarly, wearable devices devised in developed through the other PATHS-UP reserch effort will not be easily transferable to these groups. Our studies focus on the anathomy and physiology of the obese population with the ultimate goal to devising universally accessible and inclusive technologies. In progress

Abstracts, Papers, and Talks

Thrust 1 fundamental knowledge and enabling technologies.

1. Mehenur Sarwar, Chen-Zhong Li Aptamer-Based ATP Biosensor for Characterizing Engineered Heart Tissue abstract submitted to National BMES Meeting, Atlanta, GA, October 2018

2. M. Mozneb, X. Yan, P. Rodriguez, C.Z.-Li A Comparison Study on Oxygen Sensing Probes and Their Specific Application To 3D Heart Tissue Biosensors World Congress on Biosensors 2018 Jun 12-15 Miami

3. Chenzhong Li, Xuena Zhu, Mehenur Sarwar, Maedeh Mozned Nanozyme integrated POCT biosensing platform combined with a glucometer for non-glucose biomarker detection BMES 2018 Annual Meeting 2018 Oct17-20 Atlanta

4. Chenzhong Li,Maedeh Mozned New module of SPR biosensor by integration of live cell-culture system for real-time monitoring of cancer angiogenesis 28th Anniversary World Congress on Biosensors 2018 Jun 12-15 Miami

Thrust 3 fundamental knowledge and enabling technologies.

1. Mariacarla Gonzalez, Jessica Ramella-Roman, First portable, low cost Mueller matrix microscope BMES 2018 Annual Meeting abstract submitted to National BMES Meeting, Atlanta, GA, October 2018.

2. Wei-Chiang Lin, Tananant Boonya-ananta, Andres Rodriguez, and Jessica Ramella-Roman Health Wearable Devices for Patients with Obesity abstract submitted to National BMES Meeting, Atlanta, GA, October 2018.

3. Nicole Sevilla, Nidhi Suthar, Jean Marc Augustin, Daniel Wilding, Tananant Boonya-ananta, Andres Rodriguez, J.C. Ramella-Roman "TinyOx - A Wearable Muscle Oximeter for the Obese" abstract submitted to National BMES Meeting, Atlanta, GA, October 2018.

4. Jessica C. Ramella-Roman, Mariacarla Gonzalez, Joseph Chue-Sang, Karla Montejo, Karl Krup Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan A low cost portable Mueller Matrix polarimeter for the low resource settings Proceedings Volume 10485, Optics and Biophotonics in Low-Resource Settings IV; 104850X (2018) https://doi.org/10.1117/12.2290592Event: SPIE BiOS, 2018, San Francisco, California, United States

5. Mariacarla Gonzalez, Ilyas Saytashev, Camila Luna, Brittany Gonzalez, Alejandro Pinero, Manuel Perez, Sharan Ramaswamy, Jessica Ramella-Roman, "Multiphoton microscopy of ECM proteins in baboon aortic leaflet", Talk presented at SPIE BiOS, 2018, San Francisco, California, United States

6. Jessica C. Ramella-Roman, Mariacarla Gonzalez, Joseph Chue-Sang, Karla Montejo, Karl Krup Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan A low cost portable Mueller Matrix polarimeter for the low resource settings Talk presented at SPIE BiOS, 2018, San Francisco, California, United States

7. Mariacarla Gonzalez, Ilyas Saytashev, Camila Luna, Brittany Gonzalez, Alejandro Pinero, Manuel Perez, Sharan Ramaswamy, Jessica Ramella-Roman, "Multiphoton microscopy of ECM proteins in baboon aortic leaflet", Proc. SPIE 10471, Diagnostic and Therapeutic Applications of Light in Cardiology 2018, 104710Y (22 February 2018); doi: 10.1117/12.2291024; https://doi.org/10.1117/12.2291024

8. Jessica C. Ramella-Roman, 'The PATHS-UP ERC', Talk presented to NSF-ERC-ASSIST monthly meeting, February 2018.