MPL conducts research in bio-photonics and focuses on the investigation of non-invasive methodologies for diagnosis of disease based on light-tissue interaction. We are developing new imaging methodologies combining polarization sensitive techniques and non-linear microscopy to investigate anomalous organization of the extracellular matrix in several biological environments. We are utilizing these methodologies to investigate preterm labor a condition that affects 10 to 15 % of all pregnancies with severe consequences to mother and child. We are also researching early signs of Diabetic Retinopathy through the combination of imaging spectroscopy and Two-photon excitation phosphorescence lifetime imaging. We are working with TAMU, UCLA, and RICE on a new NSF funded ERC: PATHS-UP. This cross-institutional academy-industry partnership is aimed at developing affordable health devices and systems for underserved communities, with an emphasis on diabetes and cardiovascular diseases.